Go Ask Alice: Mushroom drug is studied anew.

"A third of the participants said the experience with psilocybin was the single most significant experience of their lives, and an additional 38% rated it among their top five such experiences -- akin to, say, the birth of a first child or the death of a parent. Just 8% of the Ritalin episodes were reported to be among the top five meaningful occurrences. Two months after the sessions, 79% of the participants indicated in questionnaires that their sense of well-being and satisfaction increased after the psilocybin episodes, compared with 21% for Ritalin."